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Microsoft Word - Takara09-07proof.doc
five CYP3A cDNAs have been characterized; CYP3A1 (Gonzalez et al., 1985), CYP3A2 (Gonzalez et al., 1986), CYP3A9 (Wang et al., 1996), CYP3A18 (Nagata et al., 1996; Strotkamp et al., 1995), and CYP3A23 (Kirita [...] on CYP3A9 and CYP3A18 mRNAs. Unlike other CYPs of the CYP3A subfamily, CYP3A62 was found to be predominant in the intestine rather than the liver of normal male Wistar rats. This suggests that CYP3A62 also [...] profiles of the CYP3A subfamily in the intestine of normal male Wistar rats, and previously clarified that CYP3A1 and CYP3A2 mRNAs are not detected in the intestine of rats, but CYP3A9 and CYP3A18 mRNAs are …