eldorado.tu-dortmund.de/collections/f2a2e21d-7fd2-443a-8f9f-c0f4d0d8a0fe
Lehrstuhl für Biologisch-Chemische Mikrostrukturtechnik
Gsta5, Gsta2, Hsf1, Nqo1, Apex1, Bax, Cdkn1a, Gadd45a, Mt1a, Sds, Mdm2, Myc) and one gene group which is active during cell proliferation (gene group 2: Mcm6, Cdc2, Hdc, 3-Pgdh, Cdc20, Igfbp1, Top2a, Map3k1 [...] factor receptor 2, HER-2. Therefore to counterpart this overexpression of HER-2, a therapeutic monoclonal humanized antibody (Herceptin®) directed against the extracellular domain of HER-2 was developed [...] compared to the fibroblast-like Ad-MSCs. Generated differentiated cells had higher phase I (CYP1A1/2, CYP2E1, CYP2B6, CYP3A4) and phase II activities compared to the undifferentiated cells. A strong expression …