eldorado.tu-dortmund.de/signposting/describedby/724785cb-f2a2-4f38-ba32-92aeb0a84044
A nanoporous hydrogel-based model to study chemokine gradient-driven angiogenesis under luminal flow
gradients that activate endothelial cells within a perfused parent vessel to sprout into the surrounding 3D tissue matrix. While both biochemical signals from pro-angiogenic factors, as well as mechanical cues [...] unclear whether and how both types of cues synergize. To fill this knowledge gap, here, we created a 3D biomimetic model of chemokine gradient-driven angiogenic sprouting, in which a micromolded tube inside [...] through changes in vascular permeability. en Lab on a chip; 24(20) http://creativecommons.org/licenses/by/3.0/ 540 A nanoporous hydrogel-based model to study chemokine gradient-driven angiogenesis under luminal …
