eldorado.tu-dortmund.de/items/b05f4872-853c-4d71-9d5e-7dec222b3655/full
Novel activities of 1-adamantylthiopyridines as antibacterials, antimalarials and anticancers
anticancer (MOLT-3, HepG2, HuCCA-1 and A549) activities. Results showed that all the tested derivatives selectively exerted antigrowth activity against Streptococci at 15-30 µg/mL. 3-Substituted (R) t [...] thiopyridines; 3 (R = NAc2), 5 (R = OH) and 6 (R = Br) exhibited antibacterials, antimalarials and anticancers. Significantly, 6-(1-adamantylthio) nicotinonitrile (10) is a promising antibacterial which …