eldorado.tu-dortmund.de/signposting/describedby/6f36ac6a-6b4a-4213-bbf0-2622b8a68e1e
Evaluierung der Lipidmuster S-acylierter Proteine und Azido-Ceramid Derivate zur proteomweiten Ident
expressed proteins. AIFm2, BcL-xL, Gal-1 were selected and direct interaction with variable affinities could be proved in all the cases, whereas no binding could be observed when AIFm2 and Gal-1 were titrated [...] basis of its potential implication in ceramide-mediated pathways. Binding could be confirmed for: AIFm2, APP, BUD31, Gal-1 and Gal-3, mTOR and PPT1. The specificity of those proteins for ceramide species [...] in turn, it directly regulates protein function such as the activation of the protein phosphatase PP2A. de Lipidmuster Ceramide 570 Evaluierung der Lipidmuster S-acylierter Proteine und Azido-Ceramid Derivate …